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Welcome to the PRELUDES Website!

PRELUDES (Preterm Language Development Study) is a clinical study that is committed to promoting brain and language development in preterm children and nurturing a future filled with opportunities. Join us as we strive to make a difference, one child at a time. Together, we're shaping the future of preemies everywhere.


 

Background

1 in every 10 children are born preterm. 

Here are definitions of term and the different degrees of prematurity:

  • Full-term: Live birth >37 weeks post-menstrual age
  • Moderate-late: birth at 32-37 weeks
  • Very pre-term: Birth at 28-32 weeks
  • Extremely pre-term: Birth at <28 weeks

Babies born preterm may be at higher risk for development delays and disabilities than children born at term. In particular, we have been researching how preterm birth affects language development. 


Why does this study assess language?

Language is a critical life skill. It allows children to tell adults what they want and what they need. It also allows them to share with parents what they see and understand about their world. Using language, people can communicate about the present, the past and the future. People can think and communicate about abstract ideas. Language is a major route for learning in children. It provides access to knowledge. It forms the roots for learning to read. Infants and toddlers who have strong language skills have a greater chance of succeeding in school, keeping friends, and eventually get a good job than children with early delays. 

What is the overall purpose of the PRELUDES study?

The purpose of this study is to explore how the social environment and characteristics of the brain both impact the development of language in children born preterm. The social environment includes the amount of language the child hears at home and the ways that children and families interact together. The characteristics of the brain are measured using MRI scans. 

Why is the PRELUDES study important?

The results of this study will contribute to theories of language development in all children. We do no yet understand how the environment can change the brain. We specifically hope to understand language development in children born preterm. Then we can help preterm children learn language at young ages to prevent or mitigate early delays.